In this webinar, we discussed the transcriptomic analysis of racial disparities in prostate cancer using OnRamp's ROSALIND™ platform
Prostate cancer has become the leading cause of death from cancer, more than any other form of cancer, for the male population. Prostate cancer disproportionately affects African-American men in terms of incidence, and this racial disparity surprisingly mirrors the racial differences in the circulating serum levels of vitamin D. In a recent study published in Pharmacogenomics by lead author Dr. Gary Hardiman – (Professor of Medicine and Public Health Sciences, Medical University of South Carolina) and colleagues, the findings revealed that African-American men have higher expression of genes associated with immune response and inflammation. Systems level analyses supported the concept that Inflammatory processes may contribute to disease progression in African Americans compared to European Americans. These inflammatory transcripts can be modulated by a short course of vitamin D3 supplementation
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Conclusions: In this webinar, Dr. Hardiman will demonstrate how a researcher on his team was able to complete this entire experiment, from experimental design to interpretation, using ROSALIND™(powered by OnrRamp.Bio)
ROSALIND™ is the first ever genomics analysis platform designed specifically for life science researchers and biologists. Attendees of this event can register and complete their first experiment for free: https://rosalind.onramp.bio/register
Find out how to:
Streamline RNA-seq analysis to fast track biological interpretation
Identify significantly differentially expressed genes and their association with prostate cancer
Build an entire experiment, from scratch, using no code or computer science
Who should attend?: Biologists, Genomics Core Professionals, Researchers, Drug Developers, BioInformaticians
How long is the event?: 45 minutes of content with Q&A afterwards
About the Presenter:
Dr. Hardiman has a broad background in genomics, genomics technologies, pharmacogenomics, molecular biology and bioinformatics. His research over the past 20 years in biotech and academic settings has employed functional and comparative genomics and systems biology approaches to uncover genetic targets in the context of inflammation, cancer, diabetes, cardiac disease, cystic fibrosis and HIV infection. Dr. Hardiman's research program broadly encompasses three areas: gene environment interactions in the context of endocrine disruption (using marine models and novel genomics tools), cystic fibrosis trans-membrane (CFTR) gene modifiers and environment, systems biology tool development for analysis of big data analysis such as microarray data and high-throughput sequencing (HTS) data. Currently, Dr. Hardiman serves as Scientific Director of the Center for Genomics Medicine Bioinformatics Shared Resource. He is also Head, Laboratory for Marine Systems Biology, Hollings Marine Laboratory and an Adjunct Professor & Visiting Scholar, Grice Marine Laboratory, College of Charleston.